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SMILES: Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12

InChI Key: InChIKey=KQSALEVGGXXJIU-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50111434   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139


(Homo sapiens (Human))		BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of protein kinase C

Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1


(Homo sapiens (Human))		BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a

Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3


(Homo sapiens (Human))		BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a 2.50E+4n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 5-p35nck5a

Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lyn


(Homo sapiens (Human))		BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Lyn tyrosine kinase

Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Fyn


(Homo sapiens (Human))		BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Fyn kinase

Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))		BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a>2.50E+5n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase

Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2


(Homo sapiens (Human))		BDBM50111434
PNG
(1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline | ...)
Show SMILES Cc1[nH]cnc1-c1[nH]ccc2c3ccccc3nc12
Show InChI InChI=1S/C15H12N4/c1-9-13(18-8-17-9)15-14-11(6-7-16-15)10-4-2-3-5-12(10)19-14/h2-8,16H,1H3,(H,17,18)
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n/an/a 6.00E+3n/an/an/an/an/an/a



Institute of Molecular and Cell Biology

Curated by ChEMBL


Assay Description
Inhibition of Cyclin-dependent kinase 2-cyclin A

Bioorg Med Chem Lett 12: 1129-32 (2002)


BindingDB Entry DOI: 10.7270/Q2CC1006
More data for this
Ligand-Target Pair