BDBM50111935 (R)-Thiazolidine-4-carboxylic acid [(R)-2-cyclohexylmethylsulfanyl-1-(4-phenoxy-benzylcarbamoyl)-ethyl]-amide::CHEMBL353606

SMILES: O=C(NCc1ccc(Oc2ccccc2)cc1)[C@H](CSCC1CCCCC1)NC(=O)[C@@H]1CSCN1

InChI Key: InChIKey=XDJJQUQBFLGQCK-DQEYMECFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50111935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated calcium channel subunit alpha Cav2.2 (Homo sapiens (Human))	BDBM50111935 ((R)-Thiazolidine-4-carboxylic acid [(R)-2-cyclohex...) Show SMILES O=C(NCc1ccc(Oc2ccccc2)cc1)[C@H](CSCC1CCCCC1)NC(=O)[C@@H]1CSCN1 Show InChI InChI=1S/C27H35N3O3S2/c31-26(28-15-20-11-13-23(14-12-20)33-22-9-5-2-6-10-22)25(30-27(32)24-17-35-19-29-24)18-34-16-21-7-3-1-4-8-21/h2,5-6,9-14,21,24-25,29H,1,3-4,7-8,15-19H2,(H,28,31)(H,30,32)/t24-,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of N-type calcium channels in IMR-32 cells.				Bioorg Med Chem Lett 12: 915-8 (2002) BindingDB Entry DOI: 10.7270/Q2D50M83
					More data for this Ligand-Target Pair