BDBM50112568 CHEMBL24092::N-tert-Butyl-N'-(3-chloro-4-oxazol-5-yl-phenyl)-oxalamide

SMILES: CC(C)(C)NC(=O)C(=O)Nc1ccc(-c2cnco2)c(Cl)c1

InChI Key: InChIKey=FWCWLBJSNMKVQW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50112568   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50112568 (CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...) Show SMILES CC(C)(C)NC(=O)C(=O)Nc1ccc(-c2cnco2)c(Cl)c1 Show InChI InChI=1S/C15H16ClN3O3/c1-15(2,3)19-14(21)13(20)18-9-4-5-10(11(16)6-9)12-7-17-8-22-12/h4-8H,1-3H3,(H,18,20)(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human Inosine-5'-monophosphate dehydrogenase 2				Bioorg Med Chem Lett 12: 1323-6 (2002) BindingDB Entry DOI: 10.7270/Q2NG4PX7
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (IMPDH) (Homo sapiens (Human))	BDBM50112568 (CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...) Show SMILES CC(C)(C)NC(=O)C(=O)Nc1ccc(-c2cnco2)c(Cl)c1 Show InChI InChI=1S/C15H16ClN3O3/c1-15(2,3)19-14(21)13(20)18-9-4-5-10(11(16)6-9)12-7-17-8-22-12/h4-8H,1-3H3,(H,18,20)(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Roche Discovery Welwyn Curated by ChEMBL					Assay Description Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenase				Bioorg Med Chem Lett 13: 1691-4 (2003) BindingDB Entry DOI: 10.7270/Q21N83B7
					More data for this Ligand-Target Pair
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50112568 (CHEMBL24092 | N-tert-Butyl-N'-(3-chloro-4-oxazol-5...) Show SMILES CC(C)(C)NC(=O)C(=O)Nc1ccc(-c2cnco2)c(Cl)c1 Show InChI InChI=1S/C15H16ClN3O3/c1-15(2,3)19-14(21)13(20)18-9-4-5-10(11(16)6-9)12-7-17-8-22-12/h4-8H,1-3H3,(H,18,20)(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2.				Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1
					More data for this Ligand-Target Pair