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SMILES: NC(=O)c1cccc2CN(CCCN3CCC(CC3)N3CCCCC3)C(=O)c12

InChI Key: InChIKey=IFYZHTOYLJQIFK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50113453   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Poly [ADP-ribose] polymerase 1


(Homo sapiens (Human))		BDBM50113453
PNG
(CHEMBL3605980)
Show SMILES NC(=O)c1cccc2CN(CCCN3CCC(CC3)N3CCCCC3)C(=O)c12
Show InChI InChI=1S/C22H32N4O2/c23-21(27)19-7-4-6-17-16-26(22(28)20(17)19)13-5-10-24-14-8-18(9-15-24)25-11-2-1-3-12-25/h4,6-7,18H,1-3,5,8-16H2,(H2,23,27)
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antibodypedia
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PC cid
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UniChem

Similars
PubMed
n/an/an/a 2.59E+3n/an/an/an/an/a



Nerviano Medical Sciences Srl

Curated by ChEMBL


Assay Description
Binding affinity to full length recombinant human PARP-1 by fluorescence polarization displacement assay

J Med Chem 58: 6875-98 (2015)


BindingDB Entry DOI: 10.7270/Q2JD4ZKF
More data for this
Ligand-Target Pair