BDBM50114834 8-Oxo-8-phenyl-octanoic acid hydroxyamide::CHEMBL95959::N-hydroxy-8-oxo-8-phenyloctanamide

SMILES: ONC(=O)CCCCCCC(=O)c1ccccc1

InChI Key: InChIKey=DPHGSTLAQCKOFV-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50114834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50114834 (8-Oxo-8-phenyl-octanoic acid hydroxyamide | CHEMBL...) Show SMILES ONC(=O)CCCCCCC(=O)c1ccccc1 Show InChI InChI=1S/C14H19NO3/c16-13(12-8-4-3-5-9-12)10-6-1-2-7-11-14(17)15-18/h3-5,8-9,18H,1-2,6-7,10-11H2,(H,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibition against partially purified human histone deacetylase 1 (HDAC-1)				J Med Chem 45: 2877-85 (2002) BindingDB Entry DOI: 10.7270/Q29W0DT3
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50114834 (8-Oxo-8-phenyl-octanoic acid hydroxyamide | CHEMBL...) Show SMILES ONC(=O)CCCCCCC(=O)c1ccccc1 Show InChI InChI=1S/C14H19NO3/c16-13(12-8-4-3-5-9-12)10-6-1-2-7-11-14(17)15-18/h3-5,8-9,18H,1-2,6-7,10-11H2,(H,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Homo sapiens (human) HDAC8				Citation and Details Article DOI: 10.1007/s00044-011-9571-y BindingDB Entry DOI: 10.7270/Q2KH0R79
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50114834 (8-Oxo-8-phenyl-octanoic acid hydroxyamide | CHEMBL...) Show SMILES ONC(=O)CCCCCCC(=O)c1ccccc1 Show InChI InChI=1S/C14H19NO3/c16-13(12-8-4-3-5-9-12)10-6-1-2-7-11-14(17)15-18/h3-5,8-9,18H,1-2,6-7,10-11H2,(H,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Aton Pharma, Inc Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Histone deacetylase 1				J Med Chem 46: 5097-116 (2003) Article DOI: 10.1021/jm0303094 BindingDB Entry DOI: 10.7270/Q2MP5413
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50114834 (8-Oxo-8-phenyl-octanoic acid hydroxyamide | CHEMBL...) Show SMILES ONC(=O)CCCCCCC(=O)c1ccccc1 Show InChI InChI=1S/C14H19NO3/c16-13(12-8-4-3-5-9-12)10-6-1-2-7-11-14(17)15-18/h3-5,8-9,18H,1-2,6-7,10-11H2,(H,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human HDAC1				Eur J Med Chem 44: 2868-76 (2009) Article DOI: 10.1016/j.ejmech.2008.12.008 BindingDB Entry DOI: 10.7270/Q2HM58HD
					More data for this Ligand-Target Pair