BDBM50116540 3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic acid::CHEMBL119179

SMILES: OC(=O)CCNCCCOc1ccc(Cc2ccccc2)cc1

InChI Key: InChIKey=UYZXABVIHZSXTN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50116540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50116540 (3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...) Show SMILES OC(=O)CCNCCCOc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C19H23NO3/c21-19(22)11-13-20-12-4-14-23-18-9-7-17(8-10-18)15-16-5-2-1-3-6-16/h1-3,5-10,20H,4,11-15H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human whole blood LTB-4 production (Leukotriene B-4).				J Med Chem 45: 3482-90 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KMF
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50116540 (3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...) Show SMILES OC(=O)CCNCCCOc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C19H23NO3/c21-19(22)11-13-20-12-4-14-23-18-9-7-17(8-10-18)15-16-5-2-1-3-6-16/h1-3,5-10,20H,4,11-15H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human leukotriene A4 hydrolase (LTA-4).				J Med Chem 45: 3482-90 (2002) BindingDB Entry DOI: 10.7270/Q2DV1KMF
					More data for this Ligand-Target Pair
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50116540 (3-[3-(4-Benzyl-phenoxy)-propylamino]-propionic aci...) Show SMILES OC(=O)CCNCCCOc1ccc(Cc2ccccc2)cc1 Show InChI InChI=1S/C19H23NO3/c21-19(22)11-13-20-12-4-14-23-18-9-7-17(8-10-18)15-16-5-2-1-3-6-16/h1-3,5-10,20H,4,11-15H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Gyeongsang National University (GNU) Curated by ChEMBL					Assay Description Inhibition of human leukotriene A4 hydrolase				Eur J Med Chem 46: 1593-603 (2011) Article DOI: 10.1016/j.ejmech.2011.02.007 BindingDB Entry DOI: 10.7270/Q2K64JDG
					More data for this Ligand-Target Pair