BDBM50116883 CHEMBL3612931
SMILES: [H][C@]12C[C@]1([C@@H](O)[C@@H](O)[C@@H]2n1cnc2c(NCC)nc(nc12)C#Cc1ccc(Cl)s1)C(=O)NC
InChI Key: InChIKey=QINHVPXTCNLQAU-RUZZFIIFSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine receptor A3 (Canis lupus familiaris) | BDBM50116883 (CHEMBL3612931) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to canine adenosine A3 receptor expressed in HEK293 cell membranes | ACS Med Chem Lett 6: 804-8 (2015) BindingDB Entry DOI: 10.7270/Q23R0VPF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Homo sapiens (Human)) | BDBM50116883 (CHEMBL3612931) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adenosine A3 receptor expressed in CHO cell membranes | ACS Med Chem Lett 6: 804-8 (2015) BindingDB Entry DOI: 10.7270/Q23R0VPF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine receptor A3 (Mus musculus) | BDBM50116883 (CHEMBL3612931) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL | Assay Description Binding affinity to mouse adenosine A3 receptor expressed in HEK293 cell membranes | ACS Med Chem Lett 6: 804-8 (2015) BindingDB Entry DOI: 10.7270/Q23R0VPF | |||||||||||
More data for this Ligand-Target Pair |