Found 4 hits for monomerid = 50117625 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
LIM domain kinase 1
(Homo sapiens (Human)) | BDBM50117625
(CHEMBL3613616)Show SMILES COC(=O)c1cccc(NC(=O)C2(N)CCN(CC2)c2cc(N)ncn2)c1 Show InChI InChI=1S/C18H22N6O3/c1-27-16(25)12-3-2-4-13(9-12)23-17(26)18(20)5-7-24(8-6-18)15-10-14(19)21-11-22-15/h2-4,9-11H,5-8,20H2,1H3,(H,23,26)(H2,19,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 945 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem Therapeutics N.V.
Curated by ChEMBL
| Assay Description
Inhibition of LIMK1 (unknown origin) by radiometric assay |
Bioorg Med Chem Lett 25: 4005-10 (2015)
BindingDB Entry DOI: 10.7270/Q2T72K7D |
More data for this
Ligand-Target Pair | |
LIM domain kinase 2
(Homo sapiens (Human)) | BDBM50117625
(CHEMBL3613616)Show SMILES COC(=O)c1cccc(NC(=O)C2(N)CCN(CC2)c2cc(N)ncn2)c1 Show InChI InChI=1S/C18H22N6O3/c1-27-16(25)12-3-2-4-13(9-12)23-17(26)18(20)5-7-24(8-6-18)15-10-14(19)21-11-22-15/h2-4,9-11H,5-8,20H2,1H3,(H,23,26)(H2,19,21,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem Therapeutics N.V.
Curated by ChEMBL
| Assay Description
Inhibition of ROCK2 (unknown origin) by radiometric assay |
Bioorg Med Chem Lett 25: 4005-10 (2015)
BindingDB Entry DOI: 10.7270/Q2T72K7D |
More data for this
Ligand-Target Pair | |
Rho-associated protein kinase 2
(Homo sapiens (Human)) | BDBM50117625
(CHEMBL3613616)Show SMILES COC(=O)c1cccc(NC(=O)C2(N)CCN(CC2)c2cc(N)ncn2)c1 Show InChI InChI=1S/C18H22N6O3/c1-27-16(25)12-3-2-4-13(9-12)23-17(26)18(20)5-7-24(8-6-18)15-10-14(19)21-11-22-15/h2-4,9-11H,5-8,20H2,1H3,(H,23,26)(H2,19,21,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem Therapeutics N.V.
Curated by ChEMBL
| Assay Description
Inhibition of LIMK2 (unknown origin) by radiometric assay |
Bioorg Med Chem Lett 25: 4005-10 (2015)
BindingDB Entry DOI: 10.7270/Q2T72K7D |
More data for this
Ligand-Target Pair | |
cAMP-dependent protein kinase (PKA)
(Homo sapiens (Human)) | BDBM50117625
(CHEMBL3613616)Show SMILES COC(=O)c1cccc(NC(=O)C2(N)CCN(CC2)c2cc(N)ncn2)c1 Show InChI InChI=1S/C18H22N6O3/c1-27-16(25)12-3-2-4-13(9-12)23-17(26)18(20)5-7-24(8-6-18)15-10-14(19)21-11-22-15/h2-4,9-11H,5-8,20H2,1H3,(H,23,26)(H2,19,21,22) | PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Amakem Therapeutics N.V.
Curated by ChEMBL
| Assay Description
Inhibition of LIMK1 (unknown origin) by radiometric assay |
Bioorg Med Chem Lett 25: 4005-10 (2015)
BindingDB Entry DOI: 10.7270/Q2T72K7D |
More data for this
Ligand-Target Pair | |
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