BDBM50118341 1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-naphthalen-1-yl-piperazin-1-yl)-propan-1-ol;::CHEMBL133614

SMILES: OC(CCN1CCN(CC1)c1cccc2ccccc12)c1csc2ccc(F)cc12

InChI Key: InChIKey=UBSRWNBGOMICGX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50118341   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50118341 (1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-naphthalen...) Show SMILES OC(CCN1CCN(CC1)c1cccc2ccccc12)c1csc2ccc(F)cc12 Show InChI InChI=1S/C25H25FN2OS/c26-19-8-9-25-21(16-19)22(17-30-25)24(29)10-11-27-12-14-28(15-13-27)23-7-3-5-18-4-1-2-6-20(18)23/h1-9,16-17,24,29H,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Binding affinity towards Serotonin transporter (5-HTT) in rat frontal cortex homogenates				J Med Chem 45: 4128-39 (2002) BindingDB Entry DOI: 10.7270/Q2X63M87
					More data for this Ligand-Target Pair