BDBM50118936 2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one::3-methyl-1-oxo-1-piperidin-1-ylpentan-2-aminium::CHEMBL93507
SMILES: CCC(C)C(N)C(=O)N1CCCCC1
InChI Key: InChIKey=CGPFEPGLMSJJPP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oligopeptide transporter small intestine isoform (Homo sapiens (Human)) | BDBM50118936 (2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one | 3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.62E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description Inhibition constant (Ki) for human intestinal peptide carrier | J Med Chem 46: 5725-34 (2003) Article DOI: 10.1021/jm030976x BindingDB Entry DOI: 10.7270/Q22N531C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human)) | BDBM50118936 (2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one | 3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description In vitro inhibition of porcine Dipeptidylpeptidase II. | Bioorg Med Chem Lett 12: 2825-8 (2002) BindingDB Entry DOI: 10.7270/Q279457M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human)) | BDBM50118936 (2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one | 3...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory activity of compound against Dipeptidylpeptidase II (DPP II) | J Med Chem 46: 5005-14 (2003) Article DOI: 10.1021/jm0308803 BindingDB Entry DOI: 10.7270/Q2W37X2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50118936 (2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description In vitro inhibition of human Dipeptidylpeptidase IV. | Bioorg Med Chem Lett 12: 2825-8 (2002) BindingDB Entry DOI: 10.7270/Q279457M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM50118936 (2-Amino-3-methyl-1-piperidin-1-yl-pentan-1-one | 3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Antwerp (UIA) Curated by ChEMBL | Assay Description Inhibitory activity against Dipeptidylpeptidase IV (DPP IV) | J Med Chem 46: 5005-14 (2003) Article DOI: 10.1021/jm0308803 BindingDB Entry DOI: 10.7270/Q2W37X2F | |||||||||||
More data for this Ligand-Target Pair |