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SMILES: COc1cc(NC(=O)\C=C\c2ccc3ccccc3n2)ccc1-c1cnco1

InChI Key: InChIKey=GXYOXUMUYKDWBR-PKNBQFBNSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50119044   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50119044
PNG
((E)-N-(3-Methoxy-4-oxazol-5-yl-phenyl)-3-quinolin-...)
Show SMILES COc1cc(NC(=O)\C=C\c2ccc3ccccc3n2)ccc1-c1cnco1
Show InChI InChI=1S/C22H17N3O3/c1-27-20-12-17(8-10-18(20)21-13-23-14-28-21)25-22(26)11-9-16-7-6-15-4-2-3-5-19(15)24-16/h2-14H,1H3,(H,25,26)/b11-9+
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n/an/a 57n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity of compound was evaluated against the Inosine-5'-monophosphate dehydrogenase 2

Bioorg Med Chem Lett 12: 2879-82 (2002)


BindingDB Entry DOI: 10.7270/Q29886B5
More data for this
Ligand-Target Pair