BDBM50120155 C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-difluoro-phenyl)]-methylamine::CHEMBL419179

SMILES: N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cc(F)cc(F)c1

InChI Key: InChIKey=SUUJWXLFHRQIRQ-VXKWHMMOSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50120155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50120155 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C23H22F2N2/c24-19-13-18(14-20(25)15-19)22(26)21-11-12-27(21)23(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,13-15,21-23H,11-12,26H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human ORL1 receptor was determined by using [125I]nociceptin radioligand in Chinese hamster ovary (CHO) cell membranes at a conce...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50120155 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C23H22F2N2/c24-19-13-18(14-20(25)15-19)22(26)21-11-12-27(21)23(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,13-15,21-23H,11-12,26H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor kappa 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50120155 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C23H22F2N2/c24-19-13-18(14-20(25)15-19)22(26)21-11-12-27(21)23(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,13-15,21-23H,11-12,26H2/t21-,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor mu 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0.12...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50120155 (C-[(S)-C-((S)-1-Benzhydryl-azetidin-2-yl)-C-(3,5-d...) Show SMILES N[C@H]([C@@H]1CCN1C(c1ccccc1)c1ccccc1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C23H22F2N2/c24-19-13-18(14-20(25)15-19)22(26)21-11-12-27(21)23(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,13-15,21-23H,11-12,26H2/t21-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.53E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity at human opioid receptor delta 1 was determined by using [3H]diprenorphine radioligand in CHO cell membranes at a concentration of 0...				Bioorg Med Chem Lett 12: 3157-60 (2002) BindingDB Entry DOI: 10.7270/Q2KK9C9R
					More data for this Ligand-Target Pair