BDBM50120275 3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1-yl)-N-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-propionamide::CHEMBL449084

SMILES: COc1ccc(cc1)C(=O)CNC(=O)CCn1c2CCCCc2c(=O)[nH]c1=O

InChI Key: InChIKey=DAXTYMZOIZCYBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50120275 (3-(2,4-Dioxo-3,4,5,6,7,8-hexahydro-2H-quinazolin-1...) Show SMILES COc1ccc(cc1)C(=O)CNC(=O)CCn1c2CCCCc2c(=O)[nH]c1=O Show InChI InChI=1S/C20H23N3O5/c1-28-14-8-6-13(7-9-14)17(24)12-21-18(25)10-11-23-16-5-3-2-4-15(16)19(26)22-20(23)27/h6-9H,2-5,10-12H2,1H3,(H,21,25)(H,22,26,27)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant PARP-1				Bioorg Med Chem Lett 12: 3187-90 (2002) BindingDB Entry DOI: 10.7270/Q2VX0FTT
					More data for this Ligand-Target Pair