BDBM50120993 CHEMBL3621446

SMILES: COC1CN(C1)c1nc(OC)c(NC(=O)CC(C)(C)C)c(OC)n1

InChI Key: InChIKey=OTWSPUIKNJVKBF-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50120993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel subunit Kv7.2/Kv7.3 (Homo sapiens (Human))	BDBM50120993 (CHEMBL3621446) Show SMILES COC1CN(C1)c1nc(OC)c(NC(=O)CC(C)(C)C)c(OC)n1 Show InChI InChI=1S/C16H26N4O4/c1-16(2,3)7-11(21)17-12-13(23-5)18-15(19-14(12)24-6)20-8-10(9-20)22-4/h10H,7-9H2,1-6H3,(H,17,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	961	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Activation of human Kv7.2/7.3 expressed in CHOK1 cells				Bioorg Med Chem Lett 25: 4941-4 (2015) BindingDB Entry DOI: 10.7270/Q28054FG
					More data for this Ligand-Target Pair