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SMILES: NC(=O)CC1CCN(CCOc2ccc(Cc3ccccc3)cc2)C1

InChI Key: InChIKey=NSOKRIPPJDFITD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50121015   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Leukotriene A-4 hydrolase


(Homo sapiens (Human))		BDBM50121015
PNG
(2-{1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidin-3-yl}...)
Show SMILES NC(=O)CC1CCN(CCOc2ccc(Cc3ccccc3)cc2)C1
Show InChI InChI=1S/C21H26N2O2/c22-21(24)15-19-10-11-23(16-19)12-13-25-20-8-6-18(7-9-20)14-17-4-2-1-3-5-17/h1-9,19H,10-16H2,(H2,22,24)
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n/an/a 210n/an/an/an/an/an/a



Pharmacia Corporation

Curated by ChEMBL


Assay Description
Inhibition of leukotriene A4 hydrolase in human recombinant assay

Bioorg Med Chem Lett 12: 3383-6 (2002)


BindingDB Entry DOI: 10.7270/Q2N8795W
More data for this
Ligand-Target Pair