BindingDB PrimarySearch

BDBM50123697 6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hydroxy-phenyl)-hexan-1-one::CHEMBL160817

SMILES: Oc1ccccc1C(=O)CCCCCN1CCN(CC1)c1noc2ccccc12

InChI Key: InChIKey=BWXABDUNWUIBLQ-UHFFFAOYSA-N

Data: 8 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50123697
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Serotonin (5-HT) receptor (Rattus norvegicus (rat))	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity to the rat 5-hydroxytryptamine 7 receptor				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested for 5-hydroxytryptamine 2A receptor				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested for Sigma receptor type 1				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested for Sigma receptor type 2				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	189	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity to the rat 5-hydroxytryptamine 1A receptor				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested for Dopamine receptor D2L				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	318	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested for Dopamine receptor D4				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50123697 (6-(4-Benzo[d]isoxazol-3-yl-piperazin-1-yl)-1-(2-hy...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	361	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity of compound was tested for Dopamine receptor D3				J Med Chem 46: 646-9 (2003) Article DOI: 10.1021/jm020994z BindingDB Entry DOI: 10.7270/Q23T9GKN
Università degli Studi di Bari Curated by ChEMBL					More data for this Ligand-Target Pair