BDBM50123908 Acetic acid 2-(2-phenoxy-ethoxythiocarbonyl)-phenyl-aminocarbonyl)-phenyl ester::CHEMBL354695

SMILES: CC(=O)Oc1ccccc1C(=O)N(C(=S)OCCOc1ccccc1)c1ccccc1

InChI Key: InChIKey=BJJFGZYMIPZZFS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50123908 (Acetic acid 2-(2-phenoxy-ethoxythiocarbonyl)-pheny...) Show SMILES CC(=O)Oc1ccccc1C(=O)N(C(=S)OCCOc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H21NO5S/c1-18(26)30-22-15-9-8-14-21(22)23(27)25(19-10-4-2-5-11-19)24(31)29-17-16-28-20-12-6-3-7-13-20/h2-15H,16-17H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a
Università di Genova Curated by ChEMBL					Assay Description Concentration required to achieve 50% protection of MT-4 cell from the HIV-1 induced cytopathogenicity was determined by the MTT method				J Med Chem 46: 768-81 (2003) Article DOI: 10.1021/jm0209984 BindingDB Entry DOI: 10.7270/Q2BC3XXX
					More data for this Ligand-Target Pair