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SMILES: CCCCCc1cc2c(cccc2nc1N)-c1ccc(CN)cc1

InChI Key: InChIKey=BYWLAMZEIJIRFU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124343   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 8


(Homo sapiens (Human))		BDBM50124343
PNG
(CHEMBL3622851)
Show SMILES CCCCCc1cc2c(cccc2nc1N)-c1ccc(CN)cc1
Show InChI InChI=1S/C21H25N3/c1-2-3-4-6-17-13-19-18(7-5-8-20(19)24-21(17)23)16-11-9-15(14-22)10-12-16/h5,7-13H,2-4,6,14,22H2,1H3,(H2,23,24)
PDB

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PubMed
n/an/an/an/a 699n/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Agonist activity at human TLR8 transfected in HEK293 cells assessed as activation of NF-kB by reporter gene assay

J Med Chem 58: 7833-49 (2015)


BindingDB Entry DOI: 10.7270/Q2CF9RZK
More data for this
Ligand-Target Pair