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BDBM50124361 CHEMBL3622872

SMILES: CCCNc1ncc(s1)-c1ccncc1-c1ccccc1C(C)C

InChI Key: InChIKey=ILRKBLQVNQUEQM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124361   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
LIM domain kinase 1


(Homo sapiens (Human))
BDBM50124361
PNG
(CHEMBL3622872)
Show SMILES CCCNc1ncc(s1)-c1ccncc1-c1ccccc1C(C)C
Show InChI InChI=1S/C20H23N3S/c1-4-10-22-20-23-13-19(24-20)17-9-11-21-12-18(17)16-8-6-5-7-15(16)14(2)3/h5-9,11-14H,4,10H2,1-3H3,(H,22,23)
PDB

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PC cid
PC sid
UniChem
PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



Cancer Research Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant N-terminal 6His-tagged LIMK1 (unknown origin) expressed in Sf21 cells by HTRF assay using cofilin as a substrate


J Med Chem 58: 8309-13 (2015)


BindingDB Entry DOI: 10.7270/Q27P917N
More data for this
Ligand-Target Pair