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null

SMILES: CC1=CC(C)(C)Nc2ccc-3c(C(CC=C)Oc4cccc(C#C)c-34)c12

InChI Key: InChIKey=QOOAVFNQEWFRQY-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50124615
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124615 (5-Allyl-10-ethynyl-2,2,4-trimethyl-2,5-dihydro-1H-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human glucocorticoid receptor (GR) was determined using [3H]-Dexamethasone as radioligand in SF-1 cells				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50124615 (5-Allyl-10-ethynyl-2,2,4-trimethyl-2,5-dihydro-1H-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards testosterone receptor				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50124615 (5-Allyl-10-ethynyl-2,2,4-trimethyl-2,5-dihydro-1H-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-progesterone from human Progesterone receptor A				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124615 (5-Allyl-10-ethynyl-2,2,4-trimethyl-2,5-dihydro-1H-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	59	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Transcriptional repression in HepG2 cells expressing human glucocorticoid receptor				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50124615 (5-Allyl-10-ethynyl-2,2,4-trimethyl-2,5-dihydro-1H-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of dihydrofolate reductase DHFR in Pneumocystis carinii.				J Med Chem 46: 1016-30 (2003) Article DOI: 10.1021/jm020335m BindingDB Entry DOI: 10.7270/Q2MP52NB
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair