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SMILES: Clc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)C1c1ccc2OCOc2c1

InChI Key: InChIKey=LNTRGWFSWXCQTR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125127   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50125127
PNG
((1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-beta-c...)
Show SMILES Clc1ccc(cc1)-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)C1c1ccc2OCOc2c1
Show InChI InChI=1S/C29H21ClN2O4/c30-19-8-5-17(6-9-19)23-11-12-25(36-23)29(33)32-14-13-21-20-3-1-2-4-22(20)31-27(21)28(32)18-7-10-24-26(15-18)35-16-34-24/h1-12,15,28,31H,13-14,16H2
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PubMed
 145n/an/an/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development L.L.C.

Curated by ChEMBL


Assay Description
Inhibitory activity against PDE5 from human corpus cavernosum

Bioorg Med Chem Lett 13: 761-5 (2003)


BindingDB Entry DOI: 10.7270/Q29886CM
More data for this
Ligand-Target Pair