BindingDB logo
myBDB logout

null

SMILES: Cc1cc(ccn1)-c1cccc(SCC(=O)Nc2ccc(cn2)-c2cnccn2)c1

InChI Key: InChIKey=NWTCVMKPMDPIIM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125904   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens (Human))		BDBM50125904
PNG
(CHEMBL3623878)
Show SMILES Cc1cc(ccn1)-c1cccc(SCC(=O)Nc2ccc(cn2)-c2cnccn2)c1
Show InChI InChI=1S/C23H19N5OS/c1-16-11-18(7-8-25-16)17-3-2-4-20(12-17)30-15-23(29)28-22-6-5-19(13-27-22)21-14-24-9-10-26-21/h2-14H,15H2,1H3,(H,27,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 40n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...

Bioorg Med Chem 23: 6855-68 (2015)


BindingDB Entry DOI: 10.7270/Q2J10500
More data for this
Ligand-Target Pair