BDBM50126280 1-Cinnolin-6-yl-3-m-tolyl-urea::CHEMBL26025

SMILES: Cc1cccc(NC(=O)Nc2ccc3nnccc3c2)c1

InChI Key: InChIKey=IHMPFUNGDAFLLK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50126280 (1-Cinnolin-6-yl-3-m-tolyl-urea | CHEMBL26025) Show SMILES Cc1cccc(NC(=O)Nc2ccc3nnccc3c2)c1 Show InChI InChI=1S/C16H14N4O/c1-11-3-2-4-13(9-11)18-16(21)19-14-5-6-15-12(10-14)7-8-17-20-15/h2-10H,1H3,(H2,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)				Bioorg Med Chem Lett 13: 1345-8 (2003) BindingDB Entry DOI: 10.7270/Q2CV4H3Q
					More data for this Ligand-Target Pair