BDBM50126808 3-Benzyl-8-(4-chloro-phenyl)-3-aza-bicyclo[3.2.1]octane::CHEMBL35334

SMILES: Clc1ccc(cc1)C1C2CCC1CN(Cc1ccccc1)C2

InChI Key: InChIKey=OIXPCGHWOPKIGQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50126808   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50126808 (3-Benzyl-8-(4-chloro-phenyl)-3-aza-bicyclo[3.2.1]o...) Show SMILES Clc1ccc(cc1)C1C2CCC1CN(Cc1ccccc1)C2 |THB:4:7:13.21.12:9.10,14:13:7:9.10| Show InChI InChI=1S/C20H22ClN/c21-19-10-8-16(9-11-19)20-17-6-7-18(20)14-22(13-17)12-15-4-2-1-3-5-15/h1-5,8-11,17-18,20H,6-7,12-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	95.5	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to the cocaine binding site on the dopamine transporter (DAT) in synaptosomal membrane preparations from rat stri...				J Med Chem 46: 1456-64 (2003) Article DOI: 10.1021/jm020410t BindingDB Entry DOI: 10.7270/Q2W096PJ
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50126808 (3-Benzyl-8-(4-chloro-phenyl)-3-aza-bicyclo[3.2.1]o...) Show SMILES Clc1ccc(cc1)C1C2CCC1CN(Cc1ccccc1)C2 |THB:4:7:13.21.12:9.10,14:13:7:9.10| Show InChI InChI=1S/C20H22ClN/c21-19-10-8-16(9-11-19)20-17-6-7-18(20)14-22(13-17)12-15-4-2-1-3-5-15/h1-5,8-11,17-18,20H,6-7,12-14H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	601	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of [3H]DA binding to DAT in rat striatal synaptosomes.				J Med Chem 46: 1456-64 (2003) Article DOI: 10.1021/jm020410t BindingDB Entry DOI: 10.7270/Q2W096PJ
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50126808 (3-Benzyl-8-(4-chloro-phenyl)-3-aza-bicyclo[3.2.1]o...) Show SMILES Clc1ccc(cc1)C1C2CCC1CN(Cc1ccccc1)C2 |THB:4:7:13.21.12:9.10,14:13:7:9.10| Show InChI InChI=1S/C20H22ClN/c21-19-10-8-16(9-11-19)20-17-6-7-18(20)14-22(13-17)12-15-4-2-1-3-5-15/h1-5,8-11,17-18,20H,6-7,12-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	402	n/a	n/a	n/a	n/a	n/a	n/a
School of Chemistry and Biochemistry Curated by ChEMBL					Assay Description Inhibition of [3H]citalopram binding to Serotonin transporter (5-HTT) in rat cortical tissue.				J Med Chem 46: 1456-64 (2003) Article DOI: 10.1021/jm020410t BindingDB Entry DOI: 10.7270/Q2W096PJ
					More data for this Ligand-Target Pair