BDBM50126846 CHEMBL481789

SMILES: COc1ccc-2c(SCc3cnc(nc-23)-c2ccccc2)c1

InChI Key: InChIKey=OKMYPKRTNJXZFY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126846   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50126846 (CHEMBL481789) Show SMILES COc1ccc-2c(SCc3cnc(nc-23)-c2ccccc2)c1 Show InChI InChI=1S/C18H14N2OS/c1-21-14-7-8-15-16(9-14)22-11-13-10-19-18(20-17(13)15)12-5-3-2-4-6-12/h2-10H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Pisa Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using omnia tyr peptide 7 substrate by fluorescence assay				Eur J Med Chem 103: 29-43 (2015) BindingDB Entry DOI: 10.7270/Q2G162MG
					More data for this Ligand-Target Pair