BDBM50127555 1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)-4-acetoxymethylbenzimidazole::Acetic acid 1-(2,6-difluoro-benzyl)-2-(2,6-difluoro-phenyl)-1H-benzoimidazol-4-ylmethyl ester::CHEMBL58007

SMILES: CC(=O)OCc1cccc2n(Cc3c(F)cccc3F)c(nc12)-c1c(F)cccc1F

InChI Key: InChIKey=OEFKKIOENWZRER-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50127555 (1-(2,6-difluorobenzyl)-2-(2,6-difluorophenyl)-4-ac...) Show SMILES CC(=O)OCc1cccc2n(Cc3c(F)cccc3F)c(nc12)-c1c(F)cccc1F |(10.58,-5.81,;9.25,-6.59,;7.92,-5.82,;9.26,-8.13,;7.92,-8.9,;7.93,-10.44,;6.6,-11.21,;6.6,-12.75,;7.93,-13.52,;9.27,-12.75,;10.74,-13.21,;11.23,-14.68,;10.2,-15.83,;10.69,-17.27,;12.21,-17.58,;9.68,-18.43,;8.17,-18.11,;7.68,-16.66,;8.7,-15.5,;7.21,-15.1,;11.65,-11.95,;10.73,-10.72,;9.27,-11.21,;13.18,-11.95,;13.96,-13.28,;13.19,-14.61,;15.5,-13.28,;16.26,-11.93,;15.48,-10.6,;13.94,-10.62,;13.16,-9.27,)| Show InChI InChI=1S/C23H16F4N2O2/c1-13(30)31-12-14-5-2-10-20-22(14)28-23(21-18(26)8-4-9-19(21)27)29(20)11-15-16(24)6-3-7-17(15)25/h2-10H,11-12H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibition of HIV-1 reverse transcriptase.				J Med Chem 46: 1940-7 (2003) Article DOI: 10.1021/jm020271f BindingDB Entry DOI: 10.7270/Q2610ZPC
					More data for this Ligand-Target Pair