BDBM50127604 C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine::CHEMBL305135

SMILES: NC[C@@H]1C[C@@H]1c1cnc[nH]1

InChI Key: InChIKey=LMFNLINKCDGRTE-WDSKDSINSA-N

Data: 1 KI  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50127604   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50127604 (C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...) Show SMILES NC[C@@H]1C[C@@H]1c1cnc[nH]1 Show InChI InChI=1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)/t5-,6-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Affinity against rat Histamine H3 receptor using [3H]-N-alpha-methyl histamine				J Med Chem 46: 1980-8 (2003) Article DOI: 10.1021/jm020415q BindingDB Entry DOI: 10.7270/Q2XG9QG6
					More data for this Ligand-Target Pair
Histamine H2 Receptor (Homo sapiens (Human))	BDBM50127604 (C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...) Show SMILES NC[C@@H]1C[C@@H]1c1cnc[nH]1 Show InChI InChI=1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)/t5-,6-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>0.000100	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of human Histamine H2 receptor using [3H]-tiotidine				J Med Chem 46: 1980-8 (2003) Article DOI: 10.1021/jm020415q BindingDB Entry DOI: 10.7270/Q2XG9QG6
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50127604 (C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...) Show SMILES NC[C@@H]1C[C@@H]1c1cnc[nH]1 Show InChI InChI=1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)/t5-,6-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of human Histamine H3 receptor using [3H]-N-alpha-methyl histamine				J Med Chem 46: 1980-8 (2003) Article DOI: 10.1021/jm020415q BindingDB Entry DOI: 10.7270/Q2XG9QG6
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50127604 (C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...) Show SMILES NC[C@@H]1C[C@@H]1c1cnc[nH]1 Show InChI InChI=1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)/t5-,6-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>0.000100	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of human Histamine H4 receptor				J Med Chem 46: 1980-8 (2003) Article DOI: 10.1021/jm020415q BindingDB Entry DOI: 10.7270/Q2XG9QG6
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50127604 (C-[2-(1H-Imidazol-4-yl)-cyclopropyl]-methylamine |...) Show SMILES NC[C@@H]1C[C@@H]1c1cnc[nH]1 Show InChI InChI=1S/C7H11N3/c8-2-5-1-6(5)7-3-9-4-10-7/h3-6H,1-2,8H2,(H,9,10)/t5-,6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>0.000100	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of human Histamine H1 receptor using [3H]-pyrilamine				J Med Chem 46: 1980-8 (2003) Article DOI: 10.1021/jm020415q BindingDB Entry DOI: 10.7270/Q2XG9QG6
					More data for this Ligand-Target Pair