BDBM50127655 CHEMBL3628496

SMILES: Brc1cncc(c1)N1CC2CC(C1)N2

InChI Key: InChIKey=QOZLQQMLNPWCDU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50127655 (CHEMBL3628496) Show SMILES Brc1cncc(c1)N1CC2CC(C1)N2 Show InChI InChI=1S/C10H12BrN3/c11-7-1-10(4-12-3-7)14-5-8-2-9(6-14)13-8/h1,3-4,8-9,13H,2,5-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	176	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Sassari Curated by ChEMBL					Assay Description Displacement of [125I]alpha-Bungarotoxin from alpha7 nAChR in Sprague-Dawley rat hippocampal membranes pre-incubated for 5 mins followed by overnight...				Eur J Med Chem 103: 429-37 (2015) BindingDB Entry DOI: 10.7270/Q2HT2R5N
					More data for this Ligand-Target Pair