BDBM50128374 (S)-1-(1H-Indol-4-yloxy)-3-[4-(6-methyl-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol::CHEMBL60748

SMILES: Cc1ccc2cc(sc2c1)C1CCN(C[C@H](O)COc2cccc3[nH]ccc23)CC1

InChI Key: InChIKey=IKEGNVUTXPMWNG-FQEVSTJZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50128374 ((S)-1-(1H-Indol-4-yloxy)-3-[4-(6-methyl-benzo[b]th...) Show SMILES Cc1ccc2cc(sc2c1)C1CCN(C[C@H](O)COc2cccc3[nH]ccc23)CC1 Show InChI InChI=1S/C25H28N2O2S/c1-17-5-6-19-14-25(30-24(19)13-17)18-8-11-27(12-9-18)15-20(28)16-29-23-4-2-3-22-21(23)7-10-26-22/h2-7,10,13-14,18,20,26,28H,8-9,11-12,15-16H2,1H3/t20-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity was determined towards 5-hydroxytryptamine 1A receptor receptor using [3H]-8-OH-DPAT as radioligand				Bioorg Med Chem Lett 13: 1903-5 (2003) BindingDB Entry DOI: 10.7270/Q2PV6JR6
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50128374 ((S)-1-(1H-Indol-4-yloxy)-3-[4-(6-methyl-benzo[b]th...) Show SMILES Cc1ccc2cc(sc2c1)C1CCN(C[C@H](O)COc2cccc3[nH]ccc23)CC1 Show InChI InChI=1S/C25H28N2O2S/c1-17-5-6-19-14-25(30-24(19)13-17)18-8-11-27(12-9-18)15-20(28)16-29-23-4-2-3-22-21(23)7-10-26-22/h2-7,10,13-14,18,20,26,28H,8-9,11-12,15-16H2,1H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards serotonin [5-HT] reuptake site labeled with [3H]-paroxetine as radioligand				Bioorg Med Chem Lett 13: 1903-5 (2003) BindingDB Entry DOI: 10.7270/Q2PV6JR6
					More data for this Ligand-Target Pair