BindingDB logo
myBDB logout

BDBM50128381 (S)-1-(1H-Indol-4-yloxy)-3-[4-(5-methoxy-benzo[b]thiophen-2-yl)-piperidin-1-yl]-propan-2-ol::CHEMBL57494

SMILES: COc1ccc2sc(cc2c1)C1CCN(C[C@H](O)COc2cccc3[nH]ccc23)CC1

InChI Key: InChIKey=YAZWLBWHFMOCPB-IBGZPJMESA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128381   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50128381
PNG
((S)-1-(1H-Indol-4-yloxy)-3-[4-(5-methoxy-benzo[b]t...)
Show SMILES COc1ccc2sc(cc2c1)C1CCN(C[C@H](O)COc2cccc3[nH]ccc23)CC1
Show InChI InChI=1S/C25H28N2O3S/c1-29-20-5-6-24-18(13-20)14-25(31-24)17-8-11-27(12-9-17)15-19(28)16-30-23-4-2-3-22-21(23)7-10-26-22/h2-7,10,13-14,17,19,26,28H,8-9,11-12,15-16H2,1H3/t19-/m0/s1
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 1.40n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity of the compound was determined towards 5-HT1A receptor using [3H]-8-OH-DPAT as radioligand

Bioorg Med Chem Lett 13: 1903-5 (2003)


BindingDB Entry DOI: 10.7270/Q2PV6JR6
More data for this
Ligand-Target Pair