BDBM50128386 (S)-1-[4-(5-Chloro-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol::CHEMBL57528

SMILES: Cc1cc2c(OC[C@@H](O)CN3CCC(CC3)c3cc4cc(Cl)ccc4s3)cccc2[nH]1

InChI Key: InChIKey=QLOLEBNBLJTPIF-FQEVSTJZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128386   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50128386 ((S)-1-[4-(5-Chloro-benzo[b]thiophen-2-yl)-piperidi...) Show SMILES Cc1cc2c(OC[C@@H](O)CN3CCC(CC3)c3cc4cc(Cl)ccc4s3)cccc2[nH]1 Show InChI InChI=1S/C25H27ClN2O2S/c1-16-11-21-22(27-16)3-2-4-23(21)30-15-20(29)14-28-9-7-17(8-10-28)25-13-18-12-19(26)5-6-24(18)31-25/h2-6,11-13,17,20,27,29H,7-10,14-15H2,1H3/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards serotonin [5-HT] reuptake site labeled with [3H]-paroxetine as radioligand				Bioorg Med Chem Lett 13: 1903-5 (2003) BindingDB Entry DOI: 10.7270/Q2PV6JR6
					More data for this Ligand-Target Pair