BDBM50128466 CHEMBL291513::[(2R,4S)-6-Fluoro-4-(4-fluoro-phenylamino)-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(2-fluoro-phenyl)-methanone

SMILES: C[C@@H]1C[C@H](Nc2ccc(F)cc2)c2cc(F)ccc2N1C(=O)c1ccccc1F

InChI Key: InChIKey=PQMBQNDRNVWBSB-SZNDQCEHSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128466   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ecdysone receptor (Aedes aegypti)	BDBM50128466 (CHEMBL291513 | [(2R,4S)-6-Fluoro-4-(4-fluoro-pheny...) Show SMILES C[C@@H]1C[C@H](Nc2ccc(F)cc2)c2cc(F)ccc2N1C(=O)c1ccccc1F Show InChI InChI=1S/C23H19F3N2O/c1-14-12-21(27-17-9-6-15(24)7-10-17)19-13-16(25)8-11-22(19)28(14)23(29)18-4-2-3-5-20(18)26/h2-11,13-14,21,27H,12H2,1H3/t14-,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
RHeoGene Curated by ChEMBL					Assay Description Effective concentration for ecdysone-dependent transactivation in mammalian cell line expressing Aedes aegypti ecdysone receptor				Bioorg Med Chem Lett 13: 1943-6 (2003) BindingDB Entry DOI: 10.7270/Q2NV9HN8
					More data for this Ligand-Target Pair