null
SMILES: CC(C(=O)NCc1ccc(cc1SCc1ccccc1Cl)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1
InChI Key: InChIKey=HNQQYAOPEUEXGZ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM50129016 (CHEMBL3629221) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assay | Bioorg Med Chem 23: 6844-54 (2015) BindingDB Entry DOI: 10.7270/Q2DZ0B4X | |||||||||||
More data for this Ligand-Target Pair |