BDBM50129111 (2-Chloro-5-methoxy-4-oxazol-5-yl-phenyl)-(5-phenyl-oxazol-2-yl)-amine::CHEMBL62944

SMILES: COc1cc(Nc2ncc(o2)-c2ccccc2)c(Cl)cc1-c1cnco1

InChI Key: InChIKey=LCQVSLKHQHPSGL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129111   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50129111 ((2-Chloro-5-methoxy-4-oxazol-5-yl-phenyl)-(5-pheny...) Show SMILES COc1cc(Nc2ncc(o2)-c2ccccc2)c(Cl)cc1-c1cnco1 Show InChI InChI=1S/C19H14ClN3O3/c1-24-16-8-15(14(20)7-13(16)18-9-21-11-25-18)23-19-22-10-17(26-19)12-5-3-2-4-6-12/h2-11H,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2.				Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1
					More data for this Ligand-Target Pair