BDBM50129160 9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::9-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline::CHEMBL65522

SMILES: COc1ccc2OCc3c(ccc4NC(C)(C)C=C(C)c34)-c2c1

InChI Key: InChIKey=GHHQOEGOQYZOJT-UHFFFAOYSA-N

Data: 2 KI  1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50129160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50129160 (9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...) Show SMILES COc1ccc2OCc3c(ccc4NC(C)(C)C=C(C)c34)-c2c1 |t:17| Show InChI InChI=1S/C20H21NO2/c1-12-10-20(2,3)21-17-7-6-14-15-9-13(22-4)5-8-18(15)23-11-16(14)19(12)17/h5-10,21H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	85	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129160 (9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...) Show SMILES COc1ccc2OCc3c(ccc4NC(C)(C)C=C(C)c34)-c2c1 |t:17| Show InChI InChI=1S/C20H21NO2/c1-12-10-20(2,3)21-17-7-6-14-15-9-13(22-4)5-8-18(15)23-11-16(14)19(12)17/h5-10,21H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity at human progesterone receptor.				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129160 (9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...) Show SMILES COc1ccc2OCc3c(ccc4NC(C)(C)C=C(C)c34)-c2c1 |t:17| Show InChI InChI=1S/C20H21NO2/c1-12-10-20(2,3)21-17-7-6-14-15-9-13(22-4)5-8-18(15)23-11-16(14)19(12)17/h5-10,21H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Effective concentration for human progesterone receptor in T47D human breast cancer cell				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129160 (9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...) Show SMILES COc1ccc2OCc3c(ccc4NC(C)(C)C=C(C)c34)-c2c1 |t:17| Show InChI InChI=1S/C20H21NO2/c1-12-10-20(2,3)21-17-7-6-14-15-9-13(22-4)5-8-18(15)23-11-16(14)19(12)17/h5-10,21H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human progesterone receptor activation in T47D human breast cancer cell.				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129160 (9-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...) Show SMILES COc1ccc2OCc3c(ccc4NC(C)(C)C=C(C)c34)-c2c1 |t:17| Show InChI InChI=1S/C20H21NO2/c1-12-10-20(2,3)21-17-7-6-14-15-9-13(22-4)5-8-18(15)23-11-16(14)19(12)17/h5-10,21H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity at human progesterone receptor in CV-1 cells.				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair