BDBM50129164 9-Bromo-7-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene-8-carbaldehyde::9-bromo-7-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline-8-carbaldehyde::CHEMBL66650

SMILES: CC1=CC(C)(C)Nc2ccc-3c(COc4c(F)c(C=O)c(Br)cc-34)c12

InChI Key: InChIKey=VXRUDZMHVUXDPT-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50129164 (9-Bromo-7-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(COc4c(F)c(C=O)c(Br)cc-34)c12 |t:1| Show InChI InChI=1S/C20H17BrFNO2/c1-10-7-20(2,3)23-16-5-4-11-12-6-15(21)13(8-24)18(22)19(12)25-9-14(11)17(10)16/h4-8,23H,9H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	288	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129164 (9-Bromo-7-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(COc4c(F)c(C=O)c(Br)cc-34)c12 |t:1| Show InChI InChI=1S/C20H17BrFNO2/c1-10-7-20(2,3)23-16-5-4-11-12-6-15(21)13(8-24)18(22)19(12)25-9-14(11)17(10)16/h4-8,23H,9H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding towards human progesterone receptor; Not tested				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129164 (9-Bromo-7-fluoro-2,2,4-trimethyl-2,5-dihydro-1H-6-...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(COc4c(F)c(C=O)c(Br)cc-34)c12 |t:1| Show InChI InChI=1S/C20H17BrFNO2/c1-10-7-20(2,3)23-16-5-4-11-12-6-15(21)13(8-24)18(22)19(12)25-9-14(11)17(10)16/h4-8,23H,9H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	576	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity at human progesterone receptor in CV-1 cells.				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair