BDBM50129177 2,2,4-Trimethyl-8-trifluoromethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL62872

SMILES: CC1=CC(C)(C)Nc2ccc-3c(COc4cc(ccc-34)C(F)(F)F)c12

InChI Key: InChIKey=DRJGFDIOQNMFDF-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129177   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50129177 (2,2,4-Trimethyl-8-trifluoromethyl-2,5-dihydro-1H-6...) Show SMILES CC1=CC(C)(C)Nc2ccc-3c(COc4cc(ccc-34)C(F)(F)F)c12 |t:1| Show InChI InChI=1S/C20H18F3NO/c1-11-9-19(2,3)24-16-7-6-13-14-5-4-12(20(21,22)23)8-17(14)25-10-15(13)18(11)16/h4-9,24H,10H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity at human progesterone receptor.				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair