BDBM50129546 5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H-pyrazole-3-carboxylic acid::CHEMBL302471

SMILES: OC(=O)c1cc(-c2ccc(cc2)-c2ccc(Cl)cc2Cl)n(n1)-c1ccccn1

InChI Key: InChIKey=WEHXTYFZRAPTMR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionyl-tRNA synthetase (Homo sapiens (Human))	BDBM50129546 (5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...) Show SMILES OC(=O)c1cc(-c2ccc(cc2)-c2ccc(Cl)cc2Cl)n(n1)-c1ccccn1 Show InChI InChI=1S/C21H13Cl2N3O2/c22-15-8-9-16(17(23)11-15)13-4-6-14(7-5-13)19-12-18(21(27)28)25-26(19)20-3-1-2-10-24-20/h1-12H,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)				Bioorg Med Chem Lett 13: 2231-4 (2003) BindingDB Entry DOI: 10.7270/Q24Q7TCM
					More data for this Ligand-Target Pair
Methionyl-tRNA synthetase (Homo sapiens (Human))	BDBM50129546 (5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...) Show SMILES OC(=O)c1cc(-c2ccc(cc2)-c2ccc(Cl)cc2Cl)n(n1)-c1ccccn1 Show InChI InChI=1S/C21H13Cl2N3O2/c22-15-8-9-16(17(23)11-15)13-4-6-14(7-5-13)19-12-18(21(27)28)25-26(19)20-3-1-2-10-24-20/h1-12H,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).				Bioorg Med Chem Lett 13: 2231-4 (2003) BindingDB Entry DOI: 10.7270/Q24Q7TCM
					More data for this Ligand-Target Pair
Methionyl-tRNA synthetase (Homo sapiens (Human))	BDBM50129546 (5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-2-yl-1H...) Show SMILES OC(=O)c1cc(-c2ccc(cc2)-c2ccc(Cl)cc2Cl)n(n1)-c1ccccn1 Show InChI InChI=1S/C21H13Cl2N3O2/c22-15-8-9-16(17(23)11-15)13-4-6-14(7-5-13)19-12-18(21(27)28)25-26(19)20-3-1-2-10-24-20/h1-12H,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Enterococci faecalis methionyl-tRNA synthetase (EfMetRS)				Bioorg Med Chem Lett 13: 2231-4 (2003) BindingDB Entry DOI: 10.7270/Q24Q7TCM
					More data for this Ligand-Target Pair