BDBM50130866 CHEMBL3632755
SMILES: CC(C)c1cccc(-c2cc3cc(ccc3[nH]2)C(N)=N)c1O
InChI Key: InChIKey=VEGYNLNZHWVEIZ-UHFFFAOYSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Trypsin (Homo sapiens (Human)) | BDBM50130866 (CHEMBL3632755) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited Curated by ChEMBL | Assay Description Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate | Bioorg Med Chem Lett 25: 5309-14 (2015) BindingDB Entry DOI: 10.7270/Q24B335X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Bos taurus) | BDBM50130866 (CHEMBL3632755) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited Curated by ChEMBL | Assay Description Inhibition of bovine factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrate | Bioorg Med Chem Lett 25: 5309-14 (2015) BindingDB Entry DOI: 10.7270/Q24B335X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50130866 (CHEMBL3632755) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited Curated by ChEMBL | Assay Description Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate | Bioorg Med Chem Lett 25: 5309-14 (2015) BindingDB Entry DOI: 10.7270/Q24B335X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matriptase (Homo sapiens (Human)) | BDBM50130866 (CHEMBL3632755) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrate | Bioorg Med Chem Lett 25: 5309-14 (2015) BindingDB Entry DOI: 10.7270/Q24B335X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepsin (Homo sapiens (Human)) | BDBM50130866 (CHEMBL3632755) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Aurigene Discovery Technologies Limited Curated by ChEMBL | Assay Description Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrate | Bioorg Med Chem Lett 25: 5309-14 (2015) BindingDB Entry DOI: 10.7270/Q24B335X | |||||||||||
More data for this Ligand-Target Pair |