BDBM50130998 3-[2-(4-Methoxy-benzyloxy)-phenyl]-4,5-dihydro-isoxazole-5-carboxylic acid methyl ester::CHEMBL82279
SMILES: COC(=O)C1CC(=NO1)c1ccccc1OCc1ccc(OC)cc1
InChI Key: InChIKey=NFEWQGCEMFKXSW-UHFFFAOYSA-N
Data: 1 Kd
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cystic fibrosis transmembrane conductance regulator (Rattus norvegicus) | BDBM50130998![]() (3-[2-(4-Methoxy-benzyloxy)-phenyl]-4,5-dihydro-iso...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Kd (half effective concentration) of compound against CFTR (cystic fibrosis transmembrane conductance regulator) in rat was determined | Bioorg Med Chem Lett 13: 2509-12 (2003) BindingDB Entry DOI: 10.7270/Q27D2TJS | |||||||||||
More data for this Ligand-Target Pair |