BDBM50131929 CHEMBL123952::{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-(2-naphthalen-2-yl-oxazol-4-ylmethyl)-amine

SMILES: COc1ccccc1N1CCN(CCNCc2coc(n2)-c2ccc3ccccc3c2)CC1

InChI Key: InChIKey=XISSXEYXFUJWDA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50131929 (CHEMBL123952 | {2-[4-(2-Methoxy-phenyl)-piperazin-...) Show SMILES COc1ccccc1N1CCN(CCNCc2coc(n2)-c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H30N4O2/c1-32-26-9-5-4-8-25(26)31-16-14-30(15-17-31)13-12-28-19-24-20-33-27(29-24)23-11-10-21-6-2-3-7-22(21)18-23/h2-11,18,20,28H,12-17,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D2 by [3H]spiperone displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50131929 (CHEMBL123952 | {2-[4-(2-Methoxy-phenyl)-piperazin-...) Show SMILES COc1ccccc1N1CCN(CCNCc2coc(n2)-c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H30N4O2/c1-32-26-9-5-4-8-25(26)31-16-14-30(15-17-31)13-12-28-19-24-20-33-27(29-24)23-11-10-21-6-2-3-7-22(21)18-23/h2-11,18,20,28H,12-17,19H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	295	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D3 (sf9 cells) by [3H]7-OH-DPAT displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50131929 (CHEMBL123952 | {2-[4-(2-Methoxy-phenyl)-piperazin-...) Show SMILES COc1ccccc1N1CCN(CCNCc2coc(n2)-c2ccc3ccccc3c2)CC1 Show InChI InChI=1S/C27H30N4O2/c1-32-26-9-5-4-8-25(26)31-16-14-30(15-17-31)13-12-28-19-24-20-33-27(29-24)23-11-10-21-6-2-3-7-22(21)18-23/h2-11,18,20,28H,12-17,19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum dopamine Dopamine receptor D1 by [3H]-SCH- -2339 displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair