BDBM50131991 3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-one::CHEMBL126602::cid_682361
SMILES: O=C(\C=C1\C(=O)Nc2ccccc12)c1ccccc1
InChI Key: InChIKey=HYHFPMWIIOXTBM-JLHYYAGUSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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LAP4 (Saccharomyces cerevisiae) | BDBM50131991![]() (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21R6P02 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta lactamase (Pseudomonas aeruginosa) | BDBM50131991![]() (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) | PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | >4.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2XS5T0R | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase Pfmrk (Plasmodium falciparum) | BDBM50131991![]() (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of Plasmodium falciparum cyclin dependent protein kinase, PfPK5 | J Med Chem 46: 3877-82 (2003) Article DOI: 10.1021/jm0300983 BindingDB Entry DOI: 10.7270/Q2028S9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3 (Homo sapiens (Human)) | BDBM50131991![]() (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibition of human Cyclin-dependent kinase 1 cyclin B | J Med Chem 46: 3877-82 (2003) Article DOI: 10.1021/jm0300983 BindingDB Entry DOI: 10.7270/Q2028S9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein kinase Pfmrk (Plasmodium falciparum) | BDBM50131991![]() (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) | UniProtKB/TrEMBL GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Research Curated by ChEMBL | Assay Description Inhibitory activity against Plasmodium falciparum cyclin dependent protein kinase, Pfmrk | J Med Chem 46: 3877-82 (2003) Article DOI: 10.1021/jm0300983 BindingDB Entry DOI: 10.7270/Q2028S9W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase RIPK2 (Homo sapiens (Human)) | BDBM50131991![]() (3-(2-Oxo-2-phenyl-ethylidene)-1,3-dihydro-indol-2-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2T15278 | ||||||||||||
More data for this Ligand-Target Pair |