null

SMILES: OC(=O)c1ccn[nH]1

InChI Key: InChIKey=KOPFEFZSAMLEHK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50132132   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50132132 (1H-pyrazole-3-carboxylic acid | CHEMBL128679) Show SMILES OC(=O)c1ccn[nH]1 Show InChI InChI=1S/C4H4N2O2/c7-4(8)3-1-2-5-6-3/h1-2H,(H,5,6)(H,7,8)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	594	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL					Assay Description Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.				J Med Chem 46: 3945-51 (2003) Article DOI: 10.1021/jm030888c BindingDB Entry DOI: 10.7270/Q2V988TK
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50132132 (1H-pyrazole-3-carboxylic acid | CHEMBL128679) Show SMILES OC(=O)c1ccn[nH]1 Show InChI InChI=1S/C4H4N2O2/c7-4(8)3-1-2-5-6-3/h1-2H,(H,5,6)(H,7,8)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay				Bioorg Med Chem Lett 22: 5811-3 (2012) Article DOI: 10.1016/j.bmcl.2012.07.091 BindingDB Entry DOI: 10.7270/Q2222VV7
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50132132 (1H-pyrazole-3-carboxylic acid | CHEMBL128679) Show SMILES OC(=O)c1ccn[nH]1 Show InChI InChI=1S/C4H4N2O2/c7-4(8)3-1-2-5-6-3/h1-2H,(H,5,6)(H,7,8)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair
Alcohol dehydrogenase S chain (Equus caballus)	BDBM50132132 (1H-pyrazole-3-carboxylic acid | CHEMBL128679) Show SMILES OC(=O)c1ccn[nH]1 Show InChI InChI=1S/C4H4N2O2/c7-4(8)3-1-2-5-6-3/h1-2H,(H,5,6)(H,7,8)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	6.50E+6	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of horse liver alcohol dehydrogenase using ethanol as substrate assessed as dissociation constant by spectrophotometric titration in prese...				J Med Chem 22: 356-9 (1979) Article DOI: 10.1021/jm00190a005 BindingDB Entry DOI: 10.7270/Q26T0QNZ
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM50132132 (1H-pyrazole-3-carboxylic acid | CHEMBL128679) Show SMILES OC(=O)c1ccn[nH]1 Show InChI InChI=1S/C4H4N2O2/c7-4(8)3-1-2-5-6-3/h1-2H,(H,5,6)(H,7,8)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assay				Bioorg Med Chem Lett 22: 5811-3 (2012) Article DOI: 10.1016/j.bmcl.2012.07.091 BindingDB Entry DOI: 10.7270/Q2222VV7
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50132132 (1H-pyrazole-3-carboxylic acid | CHEMBL128679) Show SMILES OC(=O)c1ccn[nH]1 Show InChI InChI=1S/C4H4N2O2/c7-4(8)3-1-2-5-6-3/h1-2H,(H,5,6)(H,7,8)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR109a expressed in human adipocytes assessed as decrease in intracellular cAMP level by HTRF assay				Bioorg Med Chem Lett 17: 5620-3 (2007) Checked by Author Article DOI: 10.1016/j.bmcl.2007.07.101 BindingDB Entry DOI: 10.7270/Q2TT4QN2
					More data for this Ligand-Target Pair