BDBM50132409 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanecarboxylic acid methyl ester::CHEMBL321276

SMILES: COC(=O)C1CCC(CC1)Nc1cnc2cc(OC)c(OC)cc2n1

InChI Key: InChIKey=FTXKUBNATJTYSH-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50132409 (4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...) Show SMILES COC(=O)C1CCC(CC1)Nc1cnc2cc(OC)c(OC)cc2n1 |(8.36,2.63,;7.03,3.39,;5.7,2.62,;5.71,1.09,;4.37,3.39,;4.36,4.92,;3.03,5.69,;1.71,4.92,;1.71,3.37,;3.03,2.62,;.38,5.68,;-.95,4.9,;-.95,3.35,;-2.28,2.57,;-3.62,3.34,;-4.95,2.57,;-6.27,3.34,;-7.62,2.57,;-7.62,1.04,;-6.27,4.89,;-7.62,5.67,;-8.95,4.89,;-4.95,5.67,;-3.62,4.89,;-2.3,5.67,)| Show InChI InChI=1S/C18H23N3O4/c1-23-15-8-13-14(9-16(15)24-2)21-17(10-19-13)20-12-6-4-11(5-7-12)18(22)25-3/h8-12H,4-7H2,1-3H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor				Bioorg Med Chem Lett 13: 3097-100 (2003) BindingDB Entry DOI: 10.7270/Q2HH6JGM
					More data for this Ligand-Target Pair
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50132409 (4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...) Show SMILES COC(=O)C1CCC(CC1)Nc1cnc2cc(OC)c(OC)cc2n1 |(8.36,2.63,;7.03,3.39,;5.7,2.62,;5.71,1.09,;4.37,3.39,;4.36,4.92,;3.03,5.69,;1.71,4.92,;1.71,3.37,;3.03,2.62,;.38,5.68,;-.95,4.9,;-.95,3.35,;-2.28,2.57,;-3.62,3.34,;-4.95,2.57,;-6.27,3.34,;-7.62,2.57,;-7.62,1.04,;-6.27,4.89,;-7.62,5.67,;-8.95,4.89,;-4.95,5.67,;-3.62,4.89,;-2.3,5.67,)| Show InChI InChI=1S/C18H23N3O4/c1-23-15-8-13-14(9-16(15)24-2)21-17(10-19-13)20-12-6-4-11(5-7-12)18(22)25-3/h8-12H,4-7H2,1-3H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	345	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor				Bioorg Med Chem Lett 13: 3097-100 (2003) BindingDB Entry DOI: 10.7270/Q2HH6JGM
					More data for this Ligand-Target Pair
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50132409 (4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...) Show SMILES COC(=O)C1CCC(CC1)Nc1cnc2cc(OC)c(OC)cc2n1 |(8.36,2.63,;7.03,3.39,;5.7,2.62,;5.71,1.09,;4.37,3.39,;4.36,4.92,;3.03,5.69,;1.71,4.92,;1.71,3.37,;3.03,2.62,;.38,5.68,;-.95,4.9,;-.95,3.35,;-2.28,2.57,;-3.62,3.34,;-4.95,2.57,;-6.27,3.34,;-7.62,2.57,;-7.62,1.04,;-6.27,4.89,;-7.62,5.67,;-8.95,4.89,;-4.95,5.67,;-3.62,4.89,;-2.3,5.67,)| Show InChI InChI=1S/C18H23N3O4/c1-23-15-8-13-14(9-16(15)24-2)21-17(10-19-13)20-12-6-4-11(5-7-12)18(22)25-3/h8-12H,4-7H2,1-3H3,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Platelet-derived growth factor receptor				Bioorg Med Chem Lett 13: 3097-100 (2003) BindingDB Entry DOI: 10.7270/Q2HH6JGM
					More data for this Ligand-Target Pair