BDBM50134005 CHEMBL137928::N,N'-(9-(2-(dimethylamino)ethylamino)acridine-2,7-diyl)bis(3-(pyrrolidin-1-yl)propanamide)::N-[9-(2-Dimethylamino-ethylamino)-7-(3-pyrrolidin-1-yl-propionylamino)-acridin-2-yl]-3-pyrrolidin-1-yl-propionamide

SMILES: CN(C)CCNc1c2cc(NC(=O)CCN3CCCC3)ccc2nc2ccc(NC(=O)CCN3CCCC3)cc12

InChI Key: InChIKey=YKRVZCROPBYFKJ-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134005 (CHEMBL137928 | N,N'-(9-(2-(dimethylamino)ethylamin...) Show SMILES CN(C)CCNc1c2cc(NC(=O)CCN3CCCC3)ccc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C31H43N7O2/c1-36(2)20-13-32-31-25-21-23(33-29(39)11-18-37-14-3-4-15-37)7-9-27(25)35-28-10-8-24(22-26(28)31)34-30(40)12-19-38-16-5-6-17-38/h7-10,21-22H,3-6,11-20H2,1-2H3,(H,32,35)(H,33,39)(H,34,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Las Villas Curated by ChEMBL					Assay Description Inhibition of telomerase in human A2780 cells by TRAP assay				Eur J Med Chem 44: 4826-40 (2009) Article DOI: 10.1016/j.ejmech.2009.07.029 BindingDB Entry DOI: 10.7270/Q20R9PHM
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50134005 (CHEMBL137928 | N,N'-(9-(2-(dimethylamino)ethylamin...) Show SMILES CN(C)CCNc1c2cc(NC(=O)CCN3CCCC3)ccc2nc2ccc(NC(=O)CCN3CCCC3)cc12 Show InChI InChI=1S/C31H43N7O2/c1-36(2)20-13-32-31-25-21-23(33-29(39)11-18-37-14-3-4-15-37)7-9-27(25)35-28-10-8-24(22-26(28)31)34-30(40)12-19-38-16-5-6-17-38/h7-10,21-22H,3-6,11-20H2,1-2H3,(H,32,35)(H,33,39)(H,34,40)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	570	n/a	n/a	n/a	n/a
University of London Curated by ChEMBL					Assay Description Inhibitory activity against human telomerase				J Med Chem 46: 4463-76 (2003) Article DOI: 10.1021/jm0308693 BindingDB Entry DOI: 10.7270/Q2RR1XN3
					More data for this Ligand-Target Pair