BDBM50135406 CHEMBL131167::[5-(1,2-Dimethyl-propylcarbamoyl)-4-methyl-thiazol-2-yl]-carbamic acid tert-butyl ester

SMILES: CC(C)C(C)NC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C

InChI Key: InChIKey=VIJXCAHIZOBABG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase LCK (Mus musculus)	BDBM50135406 (CHEMBL131167 | [5-(1,2-Dimethyl-propylcarbamoyl)-4...) Show SMILES CC(C)C(C)NC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C Show InChI InChI=1S/C15H25N3O3S/c1-8(2)9(3)16-12(19)11-10(4)17-13(22-11)18-14(20)21-15(5,6)7/h8-9H,1-7H3,(H,16,19)(H,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro inhibition of murine Lck kinase.				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50135406 (CHEMBL131167 | [5-(1,2-Dimethyl-propylcarbamoyl)-4...) Show SMILES CC(C)C(C)NC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C Show InChI InChI=1S/C15H25N3O3S/c1-8(2)9(3)16-12(19)11-10(4)17-13(22-11)18-14(20)21-15(5,6)7/h8-9H,1-7H3,(H,16,19)(H,17,18,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound human Lck(hLck) kinase				Bioorg Med Chem Lett 13: 4007-10 (2003) BindingDB Entry DOI: 10.7270/Q2CC103J
					More data for this Ligand-Target Pair