BDBM50135493 5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic acid (4-acetyl-2-methanesulfonyl-phenyl)-amide::CHEMBL335613
SMILES: CC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(c1)S(C)(=O)=O
InChI Key: InChIKey=MHXGYXIKGYLIMZ-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chymotrypsin (Homo sapiens (Human)) | BDBM50135493 (5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Toa Eiyo Ltd. Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against bovin chymotrypsin | Bioorg Med Chem Lett 13: 4085-8 (2003) BindingDB Entry DOI: 10.7270/Q2QN665P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Chymase (Homo sapiens (Human)) | BDBM50135493 (5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Toa Eiyo Ltd. Curated by ChEMBL | Assay Description In vitro inhibitory activity against human chymase | Bioorg Med Chem Lett 13: 4085-8 (2003) BindingDB Entry DOI: 10.7270/Q2QN665P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin G (Homo sapiens (Human)) | BDBM50135493 (5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Toa Eiyo Ltd. Curated by ChEMBL | Assay Description In vitro inhibitory activity of the compound against human cathepsin G | Bioorg Med Chem Lett 13: 4085-8 (2003) BindingDB Entry DOI: 10.7270/Q2QN665P | |||||||||||
More data for this Ligand-Target Pair |