BDBM50135900 5,6-Diphenyl-7-thiophen-2-yl-pyrido[2,3-d]pyrimidin-4-ylamine::CHEMBL348712
SMILES: Nc1ncnc2nc(-c3cccs3)c(-c3ccccc3)c(-c3ccccc3)c12
InChI Key: InChIKey=LLOYWJOZQUIAAS-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenosine kinase (Homo sapiens (Human)) | BDBM50135900 (5,6-Diphenyl-7-thiophen-2-yl-pyrido[2,3-d]pyrimidi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition of adenosine kinase activity in IMR-32 human neuroblastoma cells | J Med Chem 46: 5249-57 (2003) Article DOI: 10.1021/jm030327l BindingDB Entry DOI: 10.7270/Q2W66K6R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenosine kinase (Rattus norvegicus (rat)) | BDBM50135900 (5,6-Diphenyl-7-thiophen-2-yl-pyrido[2,3-d]pyrimidi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.550 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description Inhibition adenosine kinase activity in rat brain in vitro | J Med Chem 46: 5249-57 (2003) Article DOI: 10.1021/jm030327l BindingDB Entry DOI: 10.7270/Q2W66K6R | |||||||||||
More data for this Ligand-Target Pair |