BDBM50137170 2-(3-Biphenyl-2-yl-ureido)-4-chloro-benzoic acid::CHEMBL154701

SMILES: OC(=O)c1ccc(Cl)cc1NC(=O)Nc1ccccc1-c1ccccc1

InChI Key: InChIKey=DCLLIIGZJAINFF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50137170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GRIK1 (Homo sapiens (Human))	BDBM50137170 (2-(3-Biphenyl-2-yl-ureido)-4-chloro-benzoic acid |...) Show SMILES OC(=O)c1ccc(Cl)cc1NC(=O)Nc1ccccc1-c1ccccc1 Show InChI InChI=1S/C20H15ClN2O3/c21-14-10-11-16(19(24)25)18(12-14)23-20(26)22-17-9-5-4-8-15(17)13-6-2-1-3-7-13/h1-12H,(H,24,25)(H2,22,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells.				J Med Chem 46: 5834-43 (2003) Article DOI: 10.1021/jm030428j BindingDB Entry DOI: 10.7270/Q2KK9B60
					More data for this Ligand-Target Pair