BDBM50137823 ((S)-1-Formyl-3,3-dimethyl-butyl)-carbamic acid tert-butyl ester::CHEMBL94150
SMILES: CC(C)(C)C[C@H](NC(=O)OC(C)(C)C)C=O
InChI Key: InChIKey=BABQUZZMJCHKKX-VIFPVBQESA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Cathepsin K (Homo sapiens (Human)) | BDBM50137823 (((S)-1-Formyl-3,3-dimethyl-butyl)-carbamic acid te...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibiory activity against recombinant human cathepsin K | Bioorg Med Chem Lett 14: 275-8 (2003) BindingDB Entry DOI: 10.7270/Q2GM86PN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |